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concentration gradients of oxygen diffusing in a microfluidic device
Posted Feb 1, 2019, 6:04 p.m. EST Microfluidics, Bioengineering, Parameters, Variables, & Functions Version 5.4 0 Replies
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Hi! I am using the transport of diluted species to model the diffusion of oxygen in steady state. The oxygen diffuses as followed: Air--> PDMS-->water-->cells. The cells are consuming oxygen by michaelis menten Reaction. I have constant concentration at bounderies of PDMS(air). I have two major problems. 1-The solubility of oxygen in PDMS>tissue >air. I am facing oxygen concentrations that are higher than saturation! My best shot has been applying the partition coeff at the boundaries so far. Still the final results are not satisfying. 2- I get negative concentrations in some conditions. Should I add an if condition/ heaviside function/ another option for COMSOL to stop at c=0? Any ideas are appreciated. Dina
Hello Dina Dorrigiv
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