Technical Papers and Presentations

Designing and constructing a lab-on-a-chip device poses a variety of questions. Transport of all required substances, detection of the analyte and its deposition on a sensor have to be incorporated. Different strategies have been developed to achieve good coverages of the sensor, like employing electric or magnetic gradients. On the basis of a ramp like structure, the binding of the analyte to a sensor surface is being simulated. As the number of binding sites on the surface is limited, the binding probability of particles to the surface change over time. This way it is possible to measure the amount of analyte bound to the sensor and calculate capture rates as functions of time.