Technical Papers and Presentations

A key challenge in the design of medical devices that interface with blood is to minimize the likelihood of blood damage. Simulating blood flow through a medical device and estimating the likelihood of blood damage is a key step to improving performance and safety, thereby expediting ... Read More

A pneumonectomy is an invasive, high-risk surgical procedure performed to remove the right or left lung. Although this may be a life saving procedure for some patients, it has high morbidity rates and many complications post-pneumonectomy. Pneumonectomies result in the heart’s entire ... Read More

Convection is a method of heat transfer which takes advantage of a fluid’s flow over a solid. At this boundary between the solid and fluid, the convection is quantified by the convective coefficient (h) and the following boundary condition is implemented: [9] k∇T=h∆T where h is the ... Read More

Fast mixing of reagents in microfluidic devices is important for DNA sequencing, mRNA vaccine production in small-batch pharmaceutical processes, and point-of-care diagnostics. A key challenge in microfluidics is mixing reagents rapidly in a minimal amount of space. One way to do this is ... Read More

There has been a great amount of interest in nanopores as the basis for sensors and templates for preparation of biomimetic channels as well as model systems to understand transport properties at the nanoscale. The presence of surface charges on the pore walls has been shown to induce ... Read More

The exact moment approach (EMA) is adopted to predict, without any fitting parameters, the plate height curves for polystyrene microparticles of different sizes in micropillar array columns performed by hydrodynamic chromatography. The EMA allows us to decouple the contribution of ... Read More

The intestine, a muscular, tubular organ within the digestive system is responsible for the final stages of food processing. The cyclic material transport generates a shear stress on the intestinal lining known as epithelium. Recently, the application of shear stress on epithelial cells ... Read More

The separation performance of several TPMS as stationary phases in Liquid Chromatography (LC) is investigated by the implementation, in Comsol Multiphysics, of the robust and computationally efficient homogenization approach, grounded on exact local and integral moments. Specifically, ... Read More

We used Comsol simulation tools to estimate the shear stress undergone by a Hella cell trapped in a microfluidic channel. For that, we draw a 17 microns sphere blocked by 2 pillars of 10 microns in diameter. The goal of this study is to compare the maximal shear stress (τ) on the bead ... Read More

Efficient mixing and pumping of liquids at the microscale is a technology that is still to be optimized. The combination of an AC electric field with a small temperature gradient leads to a strong electrothermal flow that can be used for multiple purposes. Combining simulations and ... Read More