Biodegradation of a Magnesium Stent
Application ID: 131521
Biodegradable metallic biomaterials such as Magnesium (Mg) are gathering attention for biomedical applications due to their favorable properties.
The present model simulates dissolution of a Mg stent in a blood vessel. Due to the circumferential symmetry, only one-twelfth of the actual geometry is used in the model.
The Level Set interface is used in a first study to model the geometrical changes of the stent when subject to a local constant dissolution rate over time.
The resulting stent shapes at various stages of dissolution are then used in a second study in order to calculate the concentration of Mg ions in the tissue and vessel surrounding the stent, and the corresponding pH levels.
This model example illustrates applications of this type that would nominally be built using the following products:
however, additional products may be required to completely define and model it. Furthermore, this example may also be defined and modeled using components from the following product combinations:
- COMSOL Multiphysics® and
- either the Battery Design Module, Chemical Reaction Engineering Module, Corrosion Module, Electrochemistry Module, Electrodeposition Module, or Fuel Cell & Electrolyzer Module and
- either the CFD Module, Corrosion Module, Electrodeposition Module, Microfluidics Module, Polymer Flow Module, or Porous Media Flow Module
The combination of COMSOL® products required to model your application depends on several factors and may include boundary conditions, material properties, physics interfaces, and part libraries. Particular functionality may be common to several products. To determine the right combination of products for your modeling needs, review the Specification Chart and make use of a free evaluation license. The COMSOL Sales and Support teams are available for answering any questions you may have regarding this.