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See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.

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Non-linear DC Electrophoresis in High Electric Field Conditions

E. Ruiz-Reina [1], F. Carrique [1],
[1] University of Málaga, Málaga, Spain

Very recently, the synthesis and experimental study of a new class of highly charged polymer particles has been described, which spontaneously charge in non-aqueous low-polarity solvents [1,2]. These suspensions are an example of what is known as salt-free systems. The study of ... Read More

On the Modeling and Simulation of Electroosmotic Micropump for Biomedical Applications

M. Badran [1],
[1] Future University in Egypt, Cairo, Egypt

Non-mechanical micropumps, which does not required moving parts, have prominent role in several biomedical microsystems such as drug delivery, and lab on a chip. Electroosmotic micropump is a non-mechanical micropump that is used to move electrically neutral fluids through very small ... Read More

Nanofluidic Analyte Preconcentration Using Fluid Field-Effect Diodes

A. Eden [1], K. Scida [1], J. C. T. Eijkel [2], C. D. Meinhart [1], S. Pennathur [1],
[1] University of California, Santa Barbara, CA, USA
[2] University of Twente, Enschede, Netherlands

Introduction Throughout the field of micro- and nanoscale electrokinetics, floating bipolar electrodes (BPEs) have proven to be useful in manipulating charged ionic species and biomolecules for electroanalytical studies. The growing use of integrated electronics in working towards fully ... Read More

Study of Rotation of Ellipsoidal Particles in Combined Simple Shear Flow and Magnetic Fields

C. Wang [1], J. Zhang [1],
[1] Department of Mechanical and Aerospace Engineering, Missouri University of Science and Technology, Rolla, MO, USA

This study creates a 2D fluid-structure interaction (FSI) model to study the effect of magnetic field and particle aspect ratio on the period of rotation and symmetry of ellipsoidal paramagnetic particles. The results show that the magnetic field strength has a significant effect on the ... Read More

Dynamic Simulation of a Polymer Molecule Using COMSOL Multiphysics®: DNA Separation in a Microchannel

J. Park [1], S. Monjezi [1], M. Palaniappan [1], J. D. Jones [1], B. Behdani [1],
[1] Missouri University of Science and Technology, Rolla, MO, USA

In this study, COMSOL Multiphysics was used to simulate DNA separation within a microchannel based on the entropic trapping mechanism. The entropic trapping mechanism involves DNA molecules passing through a series of obstacles in a microchannel and different lengths of DNA exhibiting ... Read More

Microfluidic Simulation of a Separation System of T.cruzi from Blood Samples

S. L. Florez [1], M. J. Noguera [1], A. L. Campaña [1], J. C. Cruz [1], J. F. Osma [2],
[1] Department of Biomedical Engineering, University of Los Andes, Bogotá, Colombia
[2] Department of Electrical and Electronics Engineering, Microelectronics Center, University of Los Andes, Bogotá, Colombia

In 2014, it was estimated that there are between 6 to 7 million people worldwide infected by Chagas disease and approximately 25 million people are currently at risk. The parasite Trypanosoma cruzi (T. cruzi) causes this disease and according to the World Health Organization (WHO) it can ... Read More

The Effect of Fuel and Oxidant Pumping on the Performance of a Membraneless Microfluidic Fuel Cell

A. F. Tayel [1], M. A. Fathallah [1], M. M. Elsayed [1],
[1] Department of Mechanical Engineering, Alexandria University, Alexandria, Egypt

For the commercialization of membraneless microfluidic fuel cell, voltage and minimum power demand for various applications need a precise selection of fuel and oxidant flow rates to achieve the optimum cell performance. A numerical study on a membraneless microfluidic fuel cell was made ... Read More

Fluid Flow Behavior in Steady and Transient Force Medical Injection Systems

E. Gutierrez-Miravete [1], T. Langley [2],
[1] Rensselaer Polytechnic Institute - Hartford, Hartford, CT, USA
[2] Rensselaer Polytechnic Institute, Troy, NY, USA

Syringes were first conceptualized in 1650, but were invented in 1853 by Dr. Alexander Wood. As of 2011, nearly 8 billion syringes are used each year in the United States for medical purposes (not including veterinary services). These syringes are used for diseases like diabetes, ... Read More

Liquid Microlenses with Adjustable Focusing and Beam Steering For Single Cell Optogenetics

S. Berry [1], S. Redmond [1], P. Robinson [1], T. Thorsen [1], M. Rothschild [1], E. S. Boyden [2, 3]
[1] Massachusetts Institute of Technology - Lincoln Laboratory, Lexington, MA, USA
[2] Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
[3] Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA

In optogenetics research it is highly desirable to have a method that can deliver light and excite individual neurons in the brain in a controllable and single cell manner. Working toward this goal, we are developing liquid microlenses with active electronics that enable both focusing ... Read More

A Comparison of the Continuous and Discrete Approach for Liquid Manipulation

S. F. Azam [1], G. Cathcart[1],
[1] RCAST, The University of Tokyo, Tokyo, Japan

The objective of this paper is to achieve a complete and rapid efficient mixing of numerous sample in micro-scale devices of microfluidic system. The principle of microfluidics is extensively used in a number of fields such as biomedical, healthcare, biochemical, drug research and other ... Read More

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